human immortalized epidermal cell line hacat (Corning Life Sciences)
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Human Immortalized Epidermal Cell Line Hacat, supplied by Corning Life Sciences, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/human+immortalized+epidermal+cell+line+hacat/human+immortalized+epidermal+cell+line+hacat/pm40268104-54-9-22
Average 90 stars, based on 1 article reviews
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Cell Culture:Article Title: Oxidative stress-induced release of mitochondrial DNA (mtDNA) promotes the progression of vitiligo by activating the cGAS-STING signaling pathway in monocytes. Article Snippet: Vitiligo, driven by cytotoxic CD8 T cells destroying melanocytes, has recently been linked to mitochondrial DNA (mtDNA), a DAMP known to trigger innate immunity.. However, the precise role of mtDNA in vitiligo pathogenesis remains poorly understood.. In this study, we observed significantly elevated mtDNA levels in both the serum and depigmented lesions of vitiligo patients. Modification:Article Title: Oxidative stress-induced release of mitochondrial DNA (mtDNA) promotes the progression of vitiligo by activating the cGAS-STING signaling pathway in monocytes. Article Snippet: Vitiligo, driven by cytotoxic CD8 T cells destroying melanocytes, has recently been linked to mitochondrial DNA (mtDNA), a DAMP known to trigger innate immunity.. However, the precise role of mtDNA in vitiligo pathogenesis remains poorly understood.. In this study, we observed significantly elevated mtDNA levels in both the serum and depigmented lesions of vitiligo patients. |

